The CTSI provides a matrix for the promotion of clinical and translational research. Members of the CTSI come from HHC and all departments within the NYU Medical Center, Rusk Institute of Rehabilitation Medicine, NYU School of Medicine, NYU College of Dentistry, NYU College of Nursing, Nathan S. Kline Institute for Psychiatric Research, NYU Hospital for Joint Diseases, Courant Institute of Mathematical Science, Graduate School of Arts and Sciences, Polytechnic Institute of NYU, The Veterans Affairs New York Harbor Healthcare System, Steinhardt School of Education, Stern School of Business, Wagner School of Public Service, Skirball Institute of Biomolecular Medicine, Peter D. Seligman Center for Advanced Therapeutics, and Bluestone Center for Clinical Research and have their primary appointments in either the CTSI or their home Departments/Schools/Colleges.  Membership in the CTSI is by application, and the primary eligibility requirement is an interest in clinical and translational investigation.  Governance is provided by the following committees:

CTSI Executive Committee (EC). The CTSI EC, which includes the Director, Co-Director, HHC Executive Liaison, Program and Resource/Core Directors of the CTSI, Senior Faculty, Administrative Director, HHC Administrative Liaison, and a community representative, has responsibility for and authority over the space, resources and members of the CTSI. The EC meets monthly to provide financial oversight, set goals, authorize projects for utilization of CTSI resources, review performance metrics and achievement of milestones and identify and address underutilization, inappropriate use and low productivity. The EC reviews pilot projects, KL2 and TL1 applicants, as well as ongoing utilization of resources by clinical and translational studies. Each CTSI resource/core has a small committee for operations and oversight that reports to the EC through the Director of that resource/core. These committees work with the resource/core leadership to assure smooth operations, responsiveness to investigators and changes in the field, review of performance metrics and achievement of milestones. The Directors, Program Directors and the Directors of the resource/core components and sub-components of the CTSI are appointed from the participating units of NYU and HHC.

CTSI Scientific Review Committee (SRC).  This committee reviews and prioritizes projects submitted for CTSI support. It is composed of senior translational science and clinical faculty and fosters collaborative research by pointing out potential synergies between clinical and translational projects. Protocols are approved and rated according to scientific merit and resources assigned within general parameters set by the EC. A scoring system similar to that used for NIH grant reviews is utilized for the purpose of proposal review.  Minutes of the meeting are taken and provided to the CTSI EC. 

CTSI Steering Committee (SC).  The CTSI SC is chaired by Dr. Robert Berne, NYU Vice President for Health Affairs, and is composed of senior School of Medicine faculty, deans or their representatives from the participating NYU schools and colleges, and HHC representatives.  The SC oversees the operations of the CTSI through oversight of the CTSI EC. The Director and Co-Director report directly to Dr. Berne on an ad hoc basis. They also provide a written report documenting progress towards achieving the CTSI goals to Dr. Berne and the SC for the annual SC meeting. At this meeting the SC evaluates the finances, allocation of resources, securing additional funds, membership, new research directions of the CTSI, and progress in meeting the CTSI goals.

CTSI External Advisory Board. The CTSI External Advisory Board assembles yearly to provide advice to the leadership of the CTSI regarding strategic directions, successes and failures over the past year, needed improvements in process or personnel and degree of success in meeting its stated objectives.

A Central Administrative Core assures appropriate administrative support for all of the functions of the CTSI. The Core members meet monthly as a group with Deborah Chavis-Keeling, the CTSI Director for Administration & Finance, to report on each respective program’s activities. The managers and coordinators do much of the operational legwork for their cores, which allows the Directors for each program to focus on the CTSA’s “big picture". Each manager/coordinator serves on CTSI operational projects, among them the website redo team, the policy development panel, and the evaluation workgroup, which assists the Evaluation & Tracking Program in gauging the successes of the CTSI programs. Additionally, many of the managers/coordinators serve on institutional committees, providing for synergies on related projects.

The Core coordinates hiring of personnel, maintains faculty membership lists and assures the prompt communication of proposals to appropriate committees for review. With the assistance of the Medical Library, the Core maintains an archive of studies supported by and utilizing the resources of the CTSI. A Program Manager for Training & Education assures the smooth function of the education component of the CTSI.